Biotin and derivatives
![eMolecules 1204834-00-3 | Azido-PEG8-NHS ester | Broadpharm | MFCD13184949 | 564.589 | C23H40N4O12 | 97.000 | [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 500mg | 208940020](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 1204834-00-3 | Azido-PEG8-NHS ester | Broadpharm | MFCD13184949 | 564.589 | C23H40N4O12 | 97.000 | [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 500mg | 208940020
Azido-PEG8-NHS ester | Broadpharm | 1204834-00-3 | MFCD13184949 | 564.589 | C23H40N4O12 | 97.000 | [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 500mg | 208940020
Medchemexpress LLC DBCO-PEG12-NHS ester | 2093934-94-0 | 98.7% | C50H71N3O18 | 50 MG
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains a DBCO group for SPAAC with Azide groups
- Oil appearance
- Colorless to light yellow color
Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 10mg, CAS: 142439-92-7.
NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications
Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 25mg, CAS: 142439-92-7.
NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications
Medchemexpress LLC AMT-NHS | 2925268-86-4 | 98.7% | 443.47 | 25 MG
AMT-NHS is an RNA-protein crosslinker, composed of a psoralen derivative and an N-hydroxysuccinimide ester group. These groups react with RNA bases and primary amines of protein, respectively.
- Can penetrate into living yeast cells
- Crosslinks Cbf5 to H/ACA snoRNAs with high specificity
- Induces different crosslinking patterns
- Targets both single- and double-stranded regions of RNA
- Used for capturing diverse RNA-protein interactions in cells
Medchemexpress LLC Azido-PEG8-NHS ester | 1204834-00-3 | MFCD13184949 | 99.5% | 564.58 | C23H40N4O12 | 1 G
Azido-PEG8-NHS ester is an azide-functional polyethylene glycol (PEG) linker bearing an N-hydroxysuccinimide (NHS) ester reactive group used for amine bioconjugation and click chemistry in ADC and PROTAC linker synthesis.
- Enables NHS-amine coupling to primary amines.
- Azide group enables copper-catalyzed and strain-promoted click chemistry.
- PEG8 spacer increases solubility and reduces steric hindrance.
- High reported purity for reliable conjugation performance.
- Available in small laboratory pack suitable for research-scale work.
Medchemexpress LLC M-PEG-NHS ester | 92451-01-9 | MFCD01867746 | 98.0% | 2000 (average) | (C2H4O)nC7H9NO5 | 100 MG
m-PEG-NHS ester (MW 2000) is an NHS-activated methoxy poly(ethylene glycol) reagent for PEGylation of biomolecules. It reacts with primary amines to modify proteins, peptides, and small molecules to improve solubility, stability, and pharmacokinetics. Supplied as a white to off-white solid for research use, it is offered in multiple pack sizes and stored sealed away from moisture.
Medchemexpress LLC Biotin-PEG1-azide | 1204085-48-2 | 99.9% | 356.44 g/mol | C14H24N6O3S | 100 MG
Biotin-PEG1-azide is a biotin-labeled, single-unit polyethylene glycol (PEG1) azide reagent used for bioconjugation and as an ADC linker. The azide functional group enables click chemistry coupling, while the biotin tag allows affinity capture and detection.
- Biotin-labeled PEG1 azide for affinity capture
- Azide group for copper-catalyzed or strain-promoted click chemistry
- High purity suitable for bioconjugation
- Available as a 100 MG solid
- Store solid at -20 °C; in solution store at -80 °C for long-term
Medchemexpress LLC (+)-Biotin-SLC | 1864003-57-5 | ≥97.0% | 250 MG
(+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two ligands (E3 ubiquitin ligase and target protein) connected by a linker
- Exploits intracellular ubiquitin-proteasome system for target protein degradation
- For research use only
- Appearance: Solid
- Color: White to off-white
- Storage: 4°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month) under nitrogen
![Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl) | 2363756-34-5 | 98.8% | 664.81 g/mol | C28H52N6O10S | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000283161.png-250.jpg)
Medchemexpress LLC 1H-thieno[3,4-d]imidazole-4-pentanamide, N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl) | 2363756-34-5 | 98.8% | 664.81 g/mol | C28H52N6O10S | 100 MG
Biotin-PEG8-azide is a biotin-labeled polyethylene glycol (PEG8) linker with a terminal azide group used for biotinylation of macromolecules via azide-alkyne cycloaddition (click chemistry). It enables efficient conjugation for affinity capture, detection, or immobilization in biochemical assays.
- Provides a PEG8 spacer to improve solubility and reduce steric hindrance.
- Contains a terminal azide for copper-catalyzed or strain-promoted click reactions.
- Facilitates biotin labeling for high-affinity capture with streptavidin or avidin reagents.
- High purity (98.8%) suitable for research applications.
- Off-white to light yellow oil with storage recommendations for long-term stability.
eMolecules Mal-Amido-PEG11-amine TFA salt | Broadpharm |809.827 | C33H58F3N3O16 | 98.000 | OC(=O)C(F)(F)F.NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 250mg | 550804710
Mal-Amido-PEG11-amine TFA salt | Broadpharm |809.827 | C33H58F3N3O16 | 98.000 | OC(=O)C(F)(F)F.NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 250mg | 550804710
Medchemexpress LLC IL-15 Human Biotin 50ug | 50ug
IL-15 protein regulates immune cells stimulates the proliferation of NK cells T cells and B cells and promotes cytokine secretion IL-15 Protein Human (Biotinylated HEK293 Fc-Avi) is the recombinant human-derived IL-15 protein expressed by HEK293 with C-Avi C-hFc labeled tag
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 98.7% | 258.34 | C10H18N4O2S | 250 MG
Biotin hydrazide is a carbonyl-reactive biotinylation reagent used to label carbonyl-containing biomolecules such as glycoproteins and glycolipids for detection, enrichment, or affinity-capture applications.
- Reacts selectively with carbonyl groups to introduce a biotin tag.
- Suitable for biotinylation of glycoproteins and glycolipids.
- High purity (98.7%) for consistent experimental results.
- Soluble in DMSO (6.6 mg/mL) and water (2 mg/mL) with ultrasonic assistance.
- Chemical formula C10H18N4O2S and molecular weight 258.34 g/mol.
- Store powder at -20°C for long-term stability; 4°C for shorter-term storage.
Medchemexpress LLC N-Mal-N-bis(PEG2-NHS ester) | 2182601-73-4 | 98.9% | C29H38N4O15 | 50 MG
N-Mal-N-bis(PEG2-NHS ester) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds composed of two different ligands linked together; one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only and not sold to patients.
- Utilized in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Apexbio Technology LLC Sulfo-NHS-Biotin Kit (30-90 kDa) 3samples
Sulfo-NHS-Biotin Kit (30-90 kDa) is a biotinylation reagent set designed to introduce biotin molecules onto primary amines in proteins such as immunoglobulin G (IgG) The biotin molecules in this kit are activated ester derivatives (Sulfo-NHS-biotin) functioning through covalent conjugation reactions where the NHS ester group selectively reacts with primary amino groups (e g lysine residues and protein N-termini) on proteins After conjugation labeled proteins can be applied in biotin-streptavidin platforms for detection immunoassays protein immobilization and affinity purification This kit is optimized for proteins within the molecular weight range of 30-90 kDa accommodating 50-200 g protein per reaction and allows removal of excess biotin or interfering low-molecular-weight components using filtration-based purification for improved labeling quality and purity